The LWNVIVAT project focuses on finding preventive and treatment options for West Nile Fever (WNF). This disease, caused by the West Nile Virus (WNV), remains a significant public health concern in both the United States and Europe. Reported cases have increased this year, highlighting the need for continuous research and preparedness. The project aims to contribute to a global effort to combat WNV by developing effective prevention and treatment strategies.

West Nile Virus in the United States (Source: CDC)

According to the CDC, the U.S. has reported 1,410 human cases of WNV infection in 2024. Among these, 1,018 cases involve neuroinvasive disease, which affects the nervous system. The virus has spread across 49 states, reinforcing the need for ongoing public health monitoring and safety measures. The United States faces growing challenges as WNV continues to spread across various regions.

West Nile Virus in Europe (Source: European Centre for Disease Prevention and Control)

The European Centre for Disease Prevention and Control reports 1,436 WNV cases and 125 related deaths as of December 4, 2024. The virus has expanded to new areas, including Albania, Kosovo, and Slovakia, broadening its geographical reach. A total of 212 regions across Europe have reported cases this year, marking the most extensive spread in recent years. These numbers indicate that the virus is becoming more prevalent in areas that were previously unaffected.

Who Is Most Affected?

As in previous years, most cases occur in men over 65. Severe cases remain consistent, with 91% of cases requiring hospitalization. Neurological symptoms appear in 68% of cases, and the fatality rate stands at 9%. Since more severe cases are more likely to be diagnosed, high neurological involvement is expected. These figures emphasize the need for targeted interventions to protect vulnerable populations.

The Need for Action

The rising number of infections underscores the urgency of prevention and treatment efforts. As WNV spreads to more areas, developing protective measures becomes even more critical. The LWNVIVAT project plays a key role by researching new strategies to protect individuals and improve health outcomes.

Despite the increase in cases, progress continues in understanding and managing WNV. Ongoing research, including LWNVIVAT’s work, aims to ensure effective treatments and preventive solutions are available when needed.

Sources:

United States: Centers for Disease Control and Prevention (CDC)

Europe: European Centre for Disease Prevention and Control (ECDC)